Structural MRI studies employ various image analysis protocols: region-of-interest based analyses using 3D Slicer, voxel-based morphometry using Statisitical Parametric Mapping, surface based morphometry using FreeSurfer and shape analyses pipeline using FSL, SPHARM, Surfstat.
Functional MRI
fMRI studies evaluate various brain functions like working memory, facial affect processing, paired-associate learning, learned irrelevance, mental rotation, cognitive mapping, language and several others. Brain Connectivity analyses are done using both task based as well as resting state fMRI studies.
DTI
DTI studies evaluate fractional anisotropy and various diffusivity parameters (Tract Based Spatial Statistics) as well as tractography based on FSL pipeline.
MRS
Magnetic Resonance Spectroscopy studies in pipeline attempt to characterize neurochemical profile of the brain by analysing N-Acetyl Aspartate and Glutamate.
Genetics
Genetic analyses employ genotyping of functional polymorphisms in neurodevelopmentally relevant genes like IL-6, BDNF, NRG1 in order to study its association with endophenotypic & symptom profile in psychiatric disorders.
Gene Expression
Gene expression studies evaluate neuroimmunological functions in lymphocytes using relative quantification of CHRNA7, BDNF, IL-6, IGF-1 mRNAs as a neural probe- reflective of pathological brain state in psychiatric conditions.
Biochemical Assays
Biochemical assays using ELISA & FACS based cytometric bead array estimate the peripheral levels of immunological [Th1/Th2 cytokines], neurotrophic [BDNF], hormonal [Insulin, Estradiol], metabolic [Cortisol, Leptin] and other putative neurobiological markers in psychiatric disorder with possible prognostic utility.
Digit Ratio & Dermatoglyphics
Evaluation of Digit Ratio &Dermatoglyphics contribute to assessment of putative prenatal developmental status & its relationship to the pathogenesis of various psychiatric disorders.
Clinical Research
Clinical Research techniques comprise of structured interviews, symptom rating scales as well as special clinical assessments for minor physical anomalies and neurological soft signs.
Psychosocial Research
Psychosocial Research Studies involve need assessment as well as formulating intervention strategies for psychiatric disorders.
Cognition
Cognition studies employ computerized tests to evaluate working memory, facial affect processing, paired-associate learning, learned irrelevance and cognitive mapping
Eye Tracking
Eye Tracking Studies use the state-of-art EyeLink 1000 to perform saccadic, smooth pursuit and visual scan path analyses.
tDCS
tDCS studies evaluate neurobiological correlates of symptom modulation in schizophrenia.
EEG/ERP
ERP studies employ p300, p50 and related paradigms to examine schizophrenia.